Background and purpose: Focal spasticity is a significant motor disorder following stroke. Botulinum Toxin Type-A (BoNT-A) is a useful treatment for it. We evaluated kinematic modifications induced by spasticity, and whether or not there is an improvement following injection of BoNT-A.
Methods: Eight stroke patients with upper limb spasticity, showing a flexor pattern, were evaluated using kinematics before and after focal treatment with BoNT-A. A group of sex and age-matched normal volunteers acted as a control group.
Results: Repeated-measure ANOVA showed that stroke patients performed slower in comparison to the control group. Following treatment with BoNT-A there was a significant improvement in kinematics in stroke patients while in the control group performance remained unchanged.
Conclusions: Focal treatment of spasticity with Botulinum Toxin Type-A leads to an adaptive change in the upper limb of spastic stroke patients.