- Research paper
Nosocomial transmission of sporadic Creutzfeldt–Jakob disease: results from a risk-based assessment of surgical interventions
Complementary analyses by risk level
| Putative risk categories after reclassification | ||||||||||
| Unexposed* | High risk | Lower risk | Lowest risk | No risk or not reclassified | ||||||
| Time window | Subject | n (%) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) |
| Time window 1 (≥15 years) | Cases | 114 (68.3) | 0 (0.0) | 47 (28.1) | 5 (3.0) | 1 (0.6) | ||||
| MC | 642 (76.9) | 2 (0.2) | – | 132 (15.8) | 2.13 (1.39 to 3.25) | 52 (6.2) | 0.59 (0.22 to 1.55) | 7 (0.8) | 0.84 (0.10 to 6.72) | |
| UMC | 1703 (76.6) | 6 (0.3) | – | 378 (17.0) | 2.05 (1.42 to 2.96) | 117 (5.3) | 0.67 (0.26 to 1.72) | 20 (0.9) | 0.80 (0.10 to 6.62) | |
| Time window 2 (5–14 years) | Cases | 117 (70.1) | 3 (1.8) | 34 (20.4) | 7 (4.2) | 6 (3.6) | ||||
| MC | 571 (68.4) | 8 (1.0) | 1.85 (0.49 to 6.96) | 188 (22.5) | 0.88 (0.59 to 1.33) | 48 (5.7) | 0.71 (0.31 to 1.61) | 20 (2.4) | 1.47 (0.57 to 3.79) | |
| UMC | 1512 (68.0) | 11 (0.5) | 3.43 (1.01 to 11.6) | 531 (23.9) | 0.83 (0.56 to 1.24) | 123 (5.5) | 0.76 (0.34 to 1.68) | 47 (2.1) | 1.57 (0.64 to 3.85) | |
| Time window 3 (1–4 years) | Cases | 136 (81.4) | 1 (0.6) | 22 (13.2) | 7 (4.2) | 1 (0.6) | ||||
| MC | 692 (82.9) | 3 (0.4) | 1.68 (0.17 to 16.3) | 104 (12.5) | 1.07 (0.66 to 1.76) | 21 (2.5) | 1.70 (0.72 to 4.01) | 15 (1.8) | 0.32 (0.05 to 1.84) | |
| UMC | 1831 (82.3) | 12 (0.5) | 0.89 (0.12 to 6.67) | 281 (12.6) | 0.89 (0.55 to 1.43) | 59 (2.7) | 1.46 (0.65 to 3.26) | 41 (1.8) | 0.29 (0.04 to 2.07) | |
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OR for comparisons with unmatched controls (UMC) was adjusted by age, sex and country.
-
↵* Reference category. No registered surgery.
-
MC, matched controls.
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