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A 62-year-old man with neurofibromatosis type 1 presented with slowly progressive weakness in the right leg and impaired bladder function. Physical examination revealed bilateral brisk deep tendon reflexes and extensor plantar reflex. He had dozens of café au lait spots and cutaneous neurofibromas. His 12-year-old granddaughter presented with toe walking and weakness in the right hand. She showed several (>6) café au lait …
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