J Neurol Neurosurg Psychiatry doi:10.1136/jnnp-2012-304586
  • Editorial commentary

Weighty matters

  1. Geoffrey K Herkes
  1. Correspondence to Professor Geoffrey K Herkes, Department of Neurology, Royal North Shore Hospital, 66 Pacific Hwy, St Leonards, NSW 2065, Australia; gherkes{at}
  • Received 17 December 2012
  • Revised 17 December 2012
  • Accepted 19 December 2012
  • Published Online First 19 January 2013

Weighty matters

Antiepileptic drug therapy for epilepsy and mood disorders and pain management has been greatly enhanced and expanded by a growing array of therapeutic options. With choice comes the need for knowledge about the potential adverse effects of medications that may be taken lifelong. The adverse event profile of the established antiepileptic drug therapies is well established, but that of the newer agents continues to grow. Much of the known side effect profile comes from clinical trial data, which do not reflect the pattern or nature of use once an agent is marketed and available to the wider community.

Weight gain …

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