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Ultra-high field MRI: looking through the ‘macroscope’
  1. Iris D Kilsdonk1,
  2. Mike P Wattjes1,
  3. Jeroen JG Geurts2
  1. 1Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
  2. 2Department of Anatomy and Neurosciences, VU University Medical Center, Amsterdam, The Netherlands
  1. Correspondence to Dr Jeroen Geurts, Department of Anatomy and Neurosciences, VU University Medical Center, Amsterdam 1081 BT, The Netherlands; j.geurts{at}vumc.nl

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The first publications about in vivo application of ultra-high field MRI in multiple sclerosis (MS) appeared in 2008. From then on, the number of studies performed at 7 Tesla (T) has rapidly increased. The main advantage of ultra-high field MRI is its higher signal-to-noise ratio, which can be used to increase spatial resolution greatly. This has led to improved detection of subtle MS pathology, particularly in clinically relevant regions like the grey matter (GM). Another advantage of 7 T MRI is its increased sensitivity to susceptibility effects. This has been used to image additional morphological characteristics of MS lesions.1 For example, susceptibility-weighted MRI at 7 T has confirmed that MS white matter (WM) lesions are consistently …

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