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‘Surgery in ALS—don't rush in, always give it a second thought’
Pinto et al1 document that amyotrophic lateral sclerosis (ALS) patients who have surgery <3 months after clinical onset of ALS are at risk of a more rapid progression of their disease. There is also a correlation between the site of ALS onset and surgical anatomy. Functional decline was greater when surgery was performed after ALS onset, possibly because of uncertain ALS diagnosis in this group.