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Libera nos a malo
  1. C Baracchini
  1. Correspondence to Professor Claudio Baracchini, Department of Neurological Sciences, University of Padua School of Medicine, Via N. Giustiniani 5, Padova 35128, Italy; claudiobaracchini{at}

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Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in patients with MS: a solution or a harmful illusion?

Percutaneous transluminal angioplasty (PTA) of stenosed jugular and/or azygos veins,1 also known as the ‘liberation treatment’,2 has been proposed as a solution to improve the clinical outcome of MS patients with chronic cerebrospinal venous insufficiency (CCSVI).3

In their paper van Zuuren and colleagues present the summary of a Cochrane systematic review outlining the randomised controlled trials (RCTs) on this topic and conclude that there is currently no evidence to support the efficacy or safety of PTA for the treatment of CCSVI in MS patients. The authors argue in favour of well-designed RCTs which may provide further, more reliable evidence to guide clinical …

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