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Multifocal motor neuropathy: lost in conduction block?
  1. Cindy Shin-Yi Lin
  1. Correspondence to Dr Cindy Shin-Yi Lin, Faculty of Medicine, Department of Physiology, School of Medical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia; c.lin{at}unsw.edu.au, lin.csy{at}gmail.com

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How to optimise intravenous immunoglobulin (IVIg) treatment? Should IVIg treatment strategies be tailor-made with the aid of biomarkers to avoid habituation?

There has been an exponential increase in the usage of IVIg for an ever-growing number of conditions. It is a product with an excellent safety record without the side effects of steroids or other immunosuppressive agents. Despite the fact that there have been numerous recent advances in studying the mechanisms of action of IVIg in many conditions, there is still much to be learned. IVIg has had a major impact in neurology, haematology, immunology, rheumatology and dermatology. However, IVIg usage is limited by the phenomenally expensive cost and the logistical problems associated with its administration. Therefore, it is important to define its therapeutic role. …

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