Article Text

other Versions

Research paper
Measuring functional recovery in stroke patients: the responsiveness of ACTIVLIM-Stroke
  1. Charles Sèbiyo Batcho1,2,
  2. Ildéphonse Nduwimana3,
  3. Jean Olouka3,
  4. Véronique Halkin4,
  5. Toussaint Godonou Kpadonou3,
  6. Jean-Louis Thonnard1
  1. 1Institute of Neuroscience, Université catholique de Louvain, Brussels, Belgium
  2. 2Centre interdisciplinaire de recherche en réadaptation et intégration sociale (CIRRIS), Université Laval, Quebec, Canada
  3. 3Department of Rehabilitation Medicine, Faculty of Health Sciences, Université d'Abomey-Calavi, Cotonou, Benin
  4. 4Department of Rehabilitation Medicine, Centre Hospitalier Universitaire Ambroise Paré, Mons, Belgium
  1. Correspondence to Dr Charles Sèbiyo Batcho, Institute of Neuroscience, Université catholique de Louvain, 53 Avenue Mounier, COSY-B1.53.04, Brussels B-1200, Belgium; sebiyo.batcho{at}


Background and purpose To determine the efficacy of the ACTIVLIM-Stroke questionnaire in detecting changes in functional status of stroke patients.

Method Sixty-eight Benin and Belgian stroke patients participated in this 2-month longitudinal study, involving baseline and follow-up assessments. Outcome measures combined ACTIVLIM-Stroke questionnaire, Barthel Index (BI), 6-minute-walk test (6MWT) and modified Rankin scale (MRS). Responsiveness of ACTIVLIM-Stroke was investigated through different methodological approaches and compared with BI, 6MWT and MRS. Statistical analyses were performed using the paired t tests, effect size (ES) and correlation tests.

Results ACTIVLIM-Stroke detected changes in the whole sample (p<0.001, ES=0.78) and even in a subgroup of patients (p<0.001, ES=0.29) that were classified as stable according to the MRS. Moreover, ACTIVLIM-Stroke permitted the classification of patients into more discriminative groups, including those showing an important improvement (p<0.001, ES=1.87), a slight but non-clinically meaningful improvement (p<0.001, ES=0.38), and no improvement (p=0.1, ES=0.11), demonstrating its high sensitivity to change. Furthermore, there were concordant relationships between ACTIVLIM-Stroke change and any observed changes in BI, 6MWT and MRS scores (r≥0.50, p<0.001), confirming the external responsiveness of ACTVLIM-Stroke.

Conclusions ACTIVLIM-Stroke showed good responsiveness and can detect accurately clinical changes in the functional status of stroke patients. The BI and the 6MWT were also responsive and may provide complementary information while investigating change in functional status. However, in addition to being highly sensitive to change, ACTIVLIM-Stroke presents significant methodological advantages for quantifying functional changes in stroke patients.


Statistics from

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.