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Difficulties with control arms in repetitive magnetic stimulation studies
  1. Robert Caslake
  1. Correspondence to Dr Robert Caslake, Division of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK; rcaslake{at}nhs.net

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In their paper Arri and colleagues1 describe a small, randomised, crossover study that appears to demonstrate dramatic, if temporary, improvement in camptocormia in people with Parkinson's disease (PD) as a result of repetitive trans-spinal magnetic stimulation (rTSMS). While it is hard to argue that this treatment does not bear further investigation, it is not the effect of the treatment, but the lack of effect of the sham intervention that bears further discussion.

One of the factors that has made trials in repetitive magnetic stimulation, usually applied transcranially (rTMS), difficult …

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