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Review
Autoimmune choreas
  1. Francisco Cardoso
  1. Correspondence to Professor Francisco Cardoso, Professor of Neurology, Movement Disorders Unit, Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Av Pasteur 89/1107, 30150-290 Belo Horizonte, MG, Brazil; cardosofe{at}terra.com.br

Abstract

Chorea, a movement disorder characterised by a continuous flow of unpredictable muscle contractions, has a myriad of genetic and non-genetic causes. Although autoimmune processes are rare aetiology of chorea, they are relevant both for researchers and clinicians. The aim of this article is to provide a review of the epidemiology, clinical and laboratory features, pathogenesis and management of the most common autoimmune causes of chorea. Emphasis is given particularly to Sydenham's chorea, systemic lupus erythematosus, primary antiphospolipid antibody syndrome, paraneoplastic chorea and anti-N-methyl-d-aspartate receptor encephalitis.

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Footnotes

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed.

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