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Rosai-Dorfman disease presenting with multiple orbital and intracranial masses

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Abstract

Rosai-Dorfman disease is an idiopathic histocytic proliferative disorder typically characterized by painless cervical adenopathy, fever, and weight loss. Extranodal manifestations are responsible for presentation in approximately 25% of patients. Orbital involvement has been described in about 10% of patients. There have been only 16 reported cases of Rosai-Dorfman disease presenting with an intracranial mass. We report an unusual case of a patient presenting with bilateral orbital tumors as well as multiple intracranial masses. Clinical, magnetic resonance imaging, and histopathological features are discussed.

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Received: 13 October 1995 / Revised, accepted: 22 November 1995

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Resnick, D., Johnson, B. & Lovely, T. Rosai-Dorfman disease presenting with multiple orbital and intracranial masses. Acta Neuropathol 91, 554–557 (1996). https://doi.org/10.1007/s004010050466

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  • DOI: https://doi.org/10.1007/s004010050466

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