Basilar impression complicating osteogenesis imperfecta type IV: the clinical and neuroradiological findings in four cases

J Neurol Neurosurg Psychiatry. 1999 Mar;66(3):357-64. doi: 10.1136/jnnp.66.3.357.

Abstract

Objectives: To describe the clinical and neuroradiological features of basilar impression in patients with osteogenesis imperfecta type IV.

Methods: Four patients with basilar impression were ascertained in a population study of osteogenesis imperfecta. All four had detailed clinical and neuroradiological examination with both CT and MRI of the craniocervical junction and posterior fossa structures.

Results: All four showed significant compression of the posterior fossa structures and surgical decompression was performed with relief of symptoms.

Conclusion: Symptoms of cough headache and trigeminal neuralgia occurring in patients with osteogenesis imperfecta are indications for detailed clinical and neuroradiological investigation to document basilar impression.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Brain / diagnostic imaging
  • Brain / pathology
  • Female
  • Humans
  • Male
  • Osteogenesis Imperfecta / complications*
  • Osteogenesis Imperfecta / diagnostic imaging
  • Osteogenesis Imperfecta / pathology
  • Platybasia / complications*
  • Platybasia / diagnostic imaging
  • Platybasia / pathology
  • Tomography, X-Ray Computed