Abstract
The authors examined variations of serotonin transporter-linked promoter region (5-HTTLPR) functional polymorphism in 26 stroke patients with major depression and in 25 unrelated nondepressed stroke subjects of Caucasian descent. Findings indicate a significant association between 5-HTTLPR short variant genotype and poststroke major depression.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Alleles
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Depressive Disorder, Major / genetics*
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Female
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Genetic Predisposition to Disease / genetics
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Genotype
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Humans
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Male
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Middle Aged
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Polymorphism, Genetic / genetics*
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Promoter Regions, Genetic / genetics*
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Serotonin Plasma Membrane Transport Proteins / genetics*
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Statistics as Topic
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Stroke / genetics*
Substances
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SLC6A4 protein, human
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Serotonin Plasma Membrane Transport Proteins