Abstract
A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Cerebellar Neoplasms / metabolism*
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Cerebellar Neoplasms / pathology*
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Cerebellum / blood supply
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Cerebellum / metabolism*
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Cerebellum / pathology*
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Cerebrovascular Circulation / physiology
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Fluorodeoxyglucose F18 / pharmacokinetics
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Paraneoplastic Cerebellar Degeneration / metabolism*
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Paraneoplastic Cerebellar Degeneration / pathology*
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Paraneoplastic Cerebellar Degeneration / physiopathology
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Positron-Emission Tomography*
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Radiopharmaceuticals / pharmacokinetics
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Tomography, Emission-Computed, Single-Photon
Substances
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Radiopharmaceuticals
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Fluorodeoxyglucose F18