Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement

J Neurol Neurosurg Psychiatry. 2006 Sep;77(9):1092-3. doi: 10.1136/jnnp.2006.096883.

Abstract

Adult-onset copper deficiency with neurological manifestations is a newly recognised syndrome. Long-term oral copper replacement therapy has been the mainstay of treatment in the literature. A case of relapsing hypocupraemic myelopathy responsive to increased doses of copper replacement is reported. Standard doses of copper may not be sufficient for all patients.

Publication types

  • Case Reports

MeSH terms

  • Copper / deficiency*
  • Copper / therapeutic use*
  • Deficiency Diseases / complications
  • Female
  • Humans
  • Middle Aged
  • Spinal Cord Diseases / drug therapy*
  • Spinal Cord Diseases / etiology*
  • Treatment Outcome

Substances

  • Copper