Abstract
A patient with peripheral neuropathy accompanying a benign IgM anti-myelin-associated glycoprotein paraproteinemia has been treated successfully by plasmapheresis for over a year, and during this time, fluctuations in the patient's symptoms and signs have correlated with variations in the serum IgM level. These results suggest that plasmapheresis may be more beneficial for such neuropathies than indicated previously, and they add to the evidence implicating the paraprotein as the cause of the neuropathy.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Humans
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Hypergammaglobulinemia / complications*
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Hypergammaglobulinemia / immunology
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Immunoglobulin M / immunology*
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Immunoglobulin kappa-Chains
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Male
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Myelin Proteins / immunology*
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Myelin-Associated Glycoprotein
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Paraproteinemias / complications*
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Paraproteinemias / immunology
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Peripheral Nervous System Diseases / etiology*
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Peripheral Nervous System Diseases / therapy
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Plasmapheresis*
Substances
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Immunoglobulin M
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Immunoglobulin kappa-Chains
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Myelin Proteins
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Myelin-Associated Glycoprotein