Nonspecificity of semantic impairment in dementia of Alzheimer's type

Arch Neurol. 1988 Dec;45(12):1341-3. doi: 10.1001/archneur.1988.00520360059012.

Abstract

Two psychometric tests designed to evaluate "verbal fluency" and "naming" as a measure of semantic memory were presented to 18 patients with Alzheimer's-type dementia, 16 other patients with multi-infarct dementia, and 14 age-matched control subjects. The diagnosis of multi-infarct dementia and Alzheimer's-type dementia was based on the commonly accepted criteria of the Diagnostic and Statistical Manual of Mental Disorders, ed 3. Although the patients with Alzheimer and multi-infarct dementias, respectively, suffered from a comparable degree of dementia (as determined by the Mini-Mental State examination), semantic memory was not specifically impaired in Alzheimer's-type dementia as opposed to multi-infarct dementia. In contrast semantic memory was correlated with the degree of dementia in both disease entities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Alzheimer Disease / psychology*
  • Anomia / psychology
  • Aphasia / psychology
  • Dementia, Multi-Infarct / psychology
  • Female
  • Humans
  • Male
  • Memory
  • Neuropsychological Tests
  • Prospective Studies
  • Semantics*
  • Verbal Behavior