Relapsing inflammatory demyelinating polyneuropathy in a diabetic patient

Acta Neuropathol. 1986;71(1-2):94-9. doi: 10.1007/BF00687968.

Abstract

Inflammatory demyelinating polyradiculoneuropathies exhibit well-known ultrastructural lesions of the peripheral nerve, both in acute cases, i.e., Guillain-Barré syndrome, and in relapsing, sub-acute and chronic cases. We present a case of relapsing inflammatory demyelinating polyradiculoneuropathy in a diabetic patient with a biopsy exhibiting these lesions, as well as a widening of the outermost myelin lamellae in some fibers. Such associated lesions are classic in experimental inflammatory demyelinating polyradiculoneuropathies, but have not been reported in human pathology.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Animals
  • Demyelinating Diseases / pathology*
  • Diabetes Mellitus, Type 1 / pathology*
  • Diabetic Neuropathies / pathology*
  • Female
  • Humans
  • Immunoglobulins / metabolism
  • Mice
  • Microscopy, Electron
  • Middle Aged
  • Myelin Sheath / ultrastructure
  • Nerve Fibers, Myelinated / ultrastructure
  • Neuritis, Autoimmune, Experimental / pathology
  • Peripheral Nerves / ultrastructure*
  • Polyradiculoneuropathy / pathology*

Substances

  • Immunoglobulins