Inhibition of a minor pathway of L-dopa metabolism in the intestinal lumen using a decarboxylase inhibitor (Ro 4-4602)

J Pharm Pharmacol. 1974 May;26(5):377-9. doi: 10.1111/j.2042-7158.1974.tb09298.x.
No abstract available

MeSH terms

  • Animals
  • Aromatic Amino Acid Decarboxylase Inhibitors*
  • Benserazide / pharmacology
  • Catechols / metabolism
  • Chromatography, Gas
  • Decarboxylation
  • Dihydroxyphenylalanine / metabolism*
  • Hydrazines / administration & dosage
  • Hydrazines / pharmacology*
  • Hydroxylation
  • Intestinal Mucosa / metabolism*
  • Intestines / microbiology
  • Male
  • Phenylacetates / urine
  • Rats

Substances

  • Aromatic Amino Acid Decarboxylase Inhibitors
  • Catechols
  • Hydrazines
  • Phenylacetates
  • Dihydroxyphenylalanine
  • Benserazide