RT Journal Article
SR Electronic
T1 Are HLA antigens implicated in the pathogenesis of non-haemorrhagic deterioration following aneurysmal subarachnoid haemorrhage.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 1197
OP 1199
DO 10.1136/jnnp.52.10.1197
VO 52
IS 10
A1 R H Lye
A1 P A Dyer
A1 S Sheldon
A1 N Antoun
YR 1989
UL http://jnnp.bmj.com/content/52/10/1197.abstract
AB Aneursymal subarachnoid haemorrhage is frequently complicated by non-haemorrhagic deterioration. HLA typing was studied in a group of 40 patients who had sustained an aneurysmal subarachnoid haemorrhage in order to assess its ability to identify those who are likely to experience non-haemorrhagic deterioration. The antigen HLA-B7 appeared to be associated with an increased likelihood of this event supervening. Conversely, the antigen HLA-DR3, seemed to exert a "protective" influence.