RT Journal Article
SR Electronic
T1 Sequence of the superoxide dismutase 1 (SOD 1) gene in familial Parkinson's disease.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 90
OP 91
DO 10.1136/jnnp.59.1.90
VO 59
IS 1
A1 O Bandmann
A1 M B Davis
A1 C D Marsden
A1 A E Harding
YR 1995
UL http://jnnp.bmj.com/content/59/1/90.abstract
AB Mutations in the superoxide dismutase 1 (SOD1) gene have been detected in affected members of some families with familial amyotrophic lateral sclerosis. To evaluate the possibility of a shared genetic defect in amyotrophic lateral sclerosis and Parkinson's disease, the SOD1 gene was sequenced in index patients with familial Parkinson's disease from 23 families. No changes were detected.