PT - JOURNAL ARTICLE AU - J C Janssen AU - A J Larner AU - Huw Morris AU - Adolfo M Bronstein AU - Simon F Farmer TI - Upbeat nystagmus: clinicoanatomical correlation AID - 10.1136/jnnp.65.3.380 DP - 1998 Sep 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 380--381 VI - 65 IP - 3 4099 - http://jnnp.bmj.com/content/65/3/380.short 4100 - http://jnnp.bmj.com/content/65/3/380.full SO - J Neurol Neurosurg Psychiatry1998 Sep 01; 65 AB - A patient is reported on with isolated upbeating nystagmus with a linear slow phase in whom a solitary lesion, probably inflammatory, was detected radiologically in the dorsal paramedian caudal medulla, encompassing the most caudal of the perihypoglossal nuclei, the nucleus intercalatus of Staderini. The conjunction of a vestibular pattern of nystagmus with this focal lesion runs contrary to a previous suggestion that the nucleus intercalatus may act as a neural integrator for vertical conjugate eye movements.