RT Journal Article SR Electronic T1 Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications? JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 1152 OP 1153 DO 10.1136/jnnp.2006.113092 VO 78 IS 10 A1 Jens Kuhn A1 Doris Lenartz A1 Wolfgang Huff A1 SunHee Lee A1 Athanasios Koulousakis A1 Joachim Klosterkoetter A1 Volker Sturm YR 2007 UL http://jnnp.bmj.com/content/78/10/1152.abstract AB Chronic consumption of alcohol represents one of the greatest health and socioeconomic problems worldwide. We report on a 54-year-old patient with a severe anxiety disorder and secondary depressive disorder in whom bilateral deep brain stimulation (DBS) of the nucleus accumbens was carried out. Despite the absence of desired improvement in his primary disorder, we observed a remarkable although not primarily intended alleviation of the patient’s comorbid alcohol dependency. Our case report demonstrates the extremely effective treatment of alcohol dependency by means of DBS of the nucleus accumbens and may reveal new prospects in overcoming therapy resistance in dependencies in general.