ApoE alleles in relation to cerebrovascular disorders in 85 year old people
| OR (95% CI) for vascular disorders in those having at least one allele of: | |||
|---|---|---|---|
| ε2 v no ε2 | ε3 v no ε3 | ε4 v no ε4 | |
| WMLs (n=88)v no WMLs (n=101) on CT | 0.4 (0.2 to 1.0) | 0.7 (0.1 to 5.2) | 1.5 (0.8 to 2.7) |
| Infarcts (n=32) v no infarct (n=158) on CT | 1.4 (0.6 to 3.6) | 2.5 (0.3 to 20.3) | 1.2 (0.5 to 2.5) |
| Strokes or TIAs (n=46) v no strokes or TIAs (n=260) | 2.13-150 (1.1 to 4.4) | 0.6 (0.2 to 2.0) | 1.3 (0.7 to 2.4) |
↵3-150 p < 0.05 v those without the allele.
WMLs = white matter lesions; TIAs = transient ischaemic attacks.