ORs for Alzheimer’s disease, vascular dementia, and all dementias in relation to white matter lesions and possession of the apoE ε4 allele
| No dementia (n=117) n | Alzheimer’s disease (n=27) | Vascular dementia (n=37) | All dementia (n=72) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | OR | p Value | n | OR | p Value | n | OR | p Value | |||||
| No WMLs and no apoE ε4 allele (reference group) | 42 | 4 | 1.0 | 8 | 1.0 | 13 | 1.0 | ||||||
| No WMLs/at least one apoE ε4 allele | 35 | 6 | 1.8 (0.5 to 6.9) | 4 | 0.6 (0.2 to 2.2) | 11 | 1.0 (0.4 to 2.5) | ||||||
| WMLs/no apoE ε4 allele | 23 | 6 | 2.7 (0.7 to 10.7) | 7 | 1.6 (0.5 to 5.0) | 16 | 2.2 (0.9 to 5.5) | ||||||
| WMLs/at least one apoE ε4 allele | 17 | 11 | 6.8 (1.9 to 24.3) | 0.002 | 18 | 5.6 (2.0 to 15.2) | 0.0007 | 32 | 6.1 (2.6 to 14.3) | 0.00003 | |||
WMLs = white matter lesions.