Patient | Age at seizure onset | Age at PET (y) | Syndrome diagnosis | Seizure types | Interictal EEG |
---|---|---|---|---|---|
1 | 6 months | 10 | LGS after IS | IS, DA, M, GTCS | Hyps, SSW, MSW |
2 | 6 months | 5 | LGS after IS | IS, M, T | Hyps, SSW, MSW |
3 | 6 months | 10 | LGS after IS | IS, GTCS†, A, T, AtA, M† | Hyps, SSW, FR‡ |
4 | 8 months | 12 | LGS after IS | IS, T, AtA | SSW‡ |
5 | 2 months | 11 | *LGS after IS | IS, AtA, T, GTCS, M | Hyps, SSW, MSW‡ |
6 | 3 months | 7 | *LGS after IS | C, IS, T, M, M-A | MSW‡ |
7 | 3 weeks | 9 | *LGS after IS | NeoS, IS, T, GTCS | Hyps, SSW |
8 | 3 y | 11 | De novo LGS | AtA, A, NCS | SSW |
9 | 2 y | 8 | De novo LGS | GTCS, A, T, M†, CS | SSW |
10 | 5 y | 8 | De novo LGS | GTCS, A, AtA, T | SSW |
11 | 3 y | 9 | De novo LGS | GTCS, A, T, AtA, M† | SSW, FR |
12 | 4 y | 12 | De novo LGS | GTCS, A, AtA, T, NCS | SSW, MSW |
13 | 3 y | 9 | *De novo LGS | T, A, AtA, U | SSW, FR |
14 | 3 y | 5 | *De novo LGS | GTCS, AtA, U | SSW, MSW |
15 | 1 y | 5 | *De novo LGS | C, GTCS, A, M, T, AtA | SSW, FR |
16 | 3 y | 10 | *De novo LGS | A, C, T, AtA, NCS | SSW, MSW |
17 | 2 months | 10 | SMEI | C, GTCS, M-A, AtA, T, CS | SW, MSW |
18 | 5 months | 6 | SMEI | C, GTCS, M, AtA | SW, MSW |
19 | 5 months | 11 | SMEI | CS, GTCS, AtA, T, M | SW |
20 | 7 months | 12 | SMEI | CS, GTCS, AtA, CP, M, T† | SW, MSW |
21 | 3 months | 3 | SMEI | CS, GTCS, AtA, M | Diffuse slow only |
22 | 5 months | 11 | SMEI | GTCS, M, AtA, C | SW, MSW, PCR |
23 | 15 months | 4 | *SMEI | GTCS, AtA, M | SW |
24 | 12 months | 10 | *SMEI | M, GTCS, AtA, T | MSW |
25 | 11 months | 12 | *EM-AS | M, M-A, Ab, GTCS, T†, NCS | SW |
26 | 2 y | 11 | *EM-AS | M, GTCS, M-A, Ab, NCS | SW, MSW, PCR |
27 | 7 y | 12 | Unclassified | U, T, AtA | SSW, MSW |
28 | 2 y | 5 | Unclassified | GTCS, NCS, CS, M, T, AtA | SSW, MSW |
29 | 1 y | 2 | Unclassified | U, AtA, MA, M | MSW |
30 | 1 y | 8 | Unclassified | AtA, DA, T, M, C | SW, MSW, PCR |
31 | 9 months | 6 | Unclassified | GTCS, M, AtA, T | MSW |
32 | 5 months | 5 | Unclassified | GTCS, T | MSW |
IS = infantile spasms; LGS = Lennox-Gastaut syndrome; SMEI = severe mtoclonic epilepsy in infancy; EM-AS = epilepsy with myoclonic-astatic seizures; DA = drop attacks (type undetermined); M = myoclonic; GTCS = generalised tonic-clonic seizures; T = tonic; A = atonic; AtA = atypical absence; M-A = myoatonic; NeoS = neonatal seizure; NCS = non-convulsive status; CS = convulsive status; C = clonic; Ab = absence; Hyps = hypsarrythmia; SSW = slow spike and wave; MSW = multiple spike and wave; FR = fast rhythms in sleep; PCR = photoconvulsive response; * certain features in these patients were considered atypical of the syndrome (Ferrie et al 11); † implies seizure type was rare; ‡ no EEG performed during period of active spasms.