Mean (SD) baseline values
| Neuroleptic naive | Neuroleptic treated | ||||||
|---|---|---|---|---|---|---|---|
| Clozapine (n=7) | Placebo (n=11) | Clozapine (n=4) | Placebo (n=4) | ||||
| Age (y) | 43.6 (11.4) | 44.4 (10.6) | 50.5 (7.9) | 56.5 (3.9) | |||
| Disease duration (y) | 9.3 (7.5) | 7.3 (3.0) | 7.3 (3.8) | 15.3 (7.4) | |||
| AIMS | 18.7 (6.3) | 13.4 (4.2) | 20.3 (8.5) | 23.5 (5.1) | |||
| UHDRS Chorea score | 13.1 (4.9) | 10.3 (1.0) | 16.5 (4.2) | 17.8 (2.5) | |||
| UHDRS Voluntary movements | 23.7 (7.4) | 17.4 (8.9) | 30.3 (8.1) | 39.5 (5.8) | |||
| Self evaluated disability | 17.7 (13.5) | 16.9 (21.7) | 34.3 (4.9) | 50.0 (2.0)1-150 | |||
| Partner evaluated disability | 22.9 (17.4) | 12.5 (10.6) | 48.5 (14.5) | 53.8 (12.6) | |||
↵1-150 P<0.01 (Student’s t test). AIMS=Abnormal involuntary movements scale; UHDRS=unified Huntington’s disease rating scale.