Neuroleptic naive | Neuroleptic treated | ||||||
---|---|---|---|---|---|---|---|
Clozapine (n=7) | Placebo (n=11) | Clozapine (n=4) | Placebo (n=4) | ||||
Video rating of choreatic movements: | |||||||
Worse | — | 1 (9) | 2 (50) | 2 (50) | |||
Unchanged | 4 (57) | 5 (45) | 1 (25) | 1 (25) | |||
Improved | 3 (43) | 5 (45) | 1 (25) | 1 (25) | |||
Patient’s judgement of last trial week: | |||||||
Worse | 2 (29)3-150 | 1 (9) | 1 (25)3-150 | 2 (50) | |||
Unchanged | 2 (29) | 6 (55) | 2 (50) | 1 (25) | |||
Improved | 3 (43) | 4 (36) | 1 (25) | 1 (25) |
↵3-150 Four patients (two neuroleptic naive, two neuroleptic treated) experienced subjective complaints severe enough to force trial suspension (see table 4). Correcting the presented figures for their judgements, 44% of neuroleptic naive and 50% of neuroleptic treated patients would judge the last week of the trial as worse.