Clinical features and prognoses of patients with POEMS syndrome

Patient NoAge and sexDuration before treatment (months)Bone lesionClinical disability1-150Survival time (months)
Before treatmentBest during courseAt the end of follow up
Treated long term with melphalan and prednisolone:
 161M5None422> 44
 240F12Solitary433> 55
 347F5Solitary211> 49
 450M10Solitary211> 64
 532F16None211> 29
 662F15None436   50
Mean (SD)10.5 (4.3)3.0 (1.0)1.8 (0.9)2.3 (1.8)
Treated without long term chemotherapy:
 744M5None336     9
 863M7None436   17
 960M9Solitary446   11
 1056M12Multiple446   15
 1169M11None446   61
 1269M12Solitary223> 74
Mean (SD) 9.3 (2.6)3.5 (0.8)3.3 (0.7)5.5 (1.1)
  • 1-150 On the functional grading scale16; MP = melphalan-prednisolone; CP = cyclophosphamide; P = prednisolone.