Clinical characteristics of 105 patients with progressive multiple sclerosis
| TPMS (12) | SPMS (55) | PPMS (38) | P value | |
|---|---|---|---|---|
| % Women | 58.3 | 60.0 | 52.6 | NS |
| Mean age at onset (y) | 30.5 (10.9) | 29.9 (8.9) | 38.7 (7.9) | <0.011-150
†
|
| Mean age at onset of the progression (y) | 39.1 (9.4) | 40.4 (8.6) | 38.7 (7.9) | NS |
| Duration of the remitting phase (y) | 8.5 (8.0) | 10.5 (6.0) | — | NS |
| Total remission after onset bout (% patients) | 66.7 | 69.1 | — | NS |
| % With bouts during the progression | 16.7 | 25.5 | 13.2 | NS |
| Progression index (EDSS/t) | 0.48 (0.4) | 0.50 (0.3) | 0.83 (1.2) | NS1-150, P<0.05† |
↵1-150 χ2 test comparing patients with PPMS and TPMS;† χ2 test comparing patients with PPMS and SPMS. Values in parentheses are SD. TPMS = transitional multiple sclerosis; APMS = secondary progressive multiple sclerosis; PPMS = primary multiple sclerosis.