Baseline characteristics of the subjects (univariate analysis, log rank test)
| Mean (SD) | Non-demented group n=62 | Demented group n=19 | p Value |
|---|---|---|---|
| Age at baseline (y) | 65.4 (10.0) | 72.2 (8.2) | 0.0003 |
| Age at onset (y) | 56.9 (12.3) | 64.2 (12.2) | 0.005 |
| Sex (% female) | 48.4 | 26.3 | 0.15 |
| Disease duration (y) | 8.4 (6.6) | 7.9 (6.3) | 0.57 |
| Education (y) | 11.1 (4.3) | 12.0 (4.7) | 0.64 |
| UPDRS III | 16.5 (4.9) | 20.1 (9.5) | 0.01 |
| Hoehn and Yahr | 1.73 (1.28) | 1.95 (0.62) | 0.39 |
| CES depression | 19.8 (9.5) | 17.3 (7.7) | 0.58 |
| Zung anxiety | 39.4 (8.3) | 40.1 (6.9) | 0.28 |
| Folstein MMSE | 27.6 (1.7) | 25.7 (2.7) | 0.004 |
| Psychotic adverse | 9 | 10 | 0.0006 |
| Events n (%) | (14.5) | (52.6) |
UPDRS III = Unified Parkinson’s disease rating scale: motor examination score; MMS= mini mental state examination.