Comparison of timed variables before (off) and after (on) administration of oral levodopa and subcutaneous apomorphine for three bolus consistencies
| Semisolids | Thin fluids | Solids | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Levodopa | Apomorphine | Levodopa | Apomorphine | Levodopa | Apomorphine | ||||||||||||
| Off | On | Off | On | Off | On | Off | On | Off | On | Off | On | ||||||
| Oral preparatory phase | 0.40 (0.09) | 0.202-150 (0.04) | 0.42 (0.67) | 0.31 (0.08) | 1.30 (0.44) | 0.652-150 (0.35) | 2.3 (0.8) | 1.75 (0.57) | 0.34 (0.08) | 0.30 (0.07) | 0.29 (0.05) | 0.49 (0.19) | |||||
| Oral phase | 4.44 (1.21) | 4.20 (1.01) | 5.2 (0.87) | 5.90 (1.13) | 1.77 (0.39) | 2.28 (0.93) | 3.75 (1.38) | 3.61 (0.82) | 18.24 (2.69) | 24.012-150 (2.18) | 42.37 (21.4) | 22.0 (1.95) | |||||
| Pharyngeal phase time | 1.70 (0.47) | 1.64 (0.44) | 2.23 (0.51) | 2.72 (0.73) | 1.41 (0.52) | 0.63 (0.22) | 1.28 (0.56) | 1.08 (0.37) | 4.7 (1.95) | 2.7 (1.02) | 3.65 (0.95) | 3.30 (1.24) | |||||
| Rapid pharyngeal transit | 0.28 (0.03) | 0.29 (0.05) | 0.31 (0.05) | 0.262-150 (0.05) | 0.36 (0.07) | 0.27 (0.03) | 0.28 (0.3) | 0.27 (0.03) | 0.39 (0.06) | 0.43 (0.1) | 0.38 (0.05) | 0.31 (0.05) | |||||
| Total initial swallow | 6.79 (1.32) | 5.78 (1.03) | 7.69 (0.93) | 7.99 (1.12) | 4.01 (0.84) | 3.27 (0.88) | 7.18 (1.94) | 6.42 (1.1) | 19.99 (2.92) | 27.42-150 (2.55) | 26.34 (3.17) | 26.72 (2.88) | |||||
| Complete swallow | 19.4 (2.24) | 15.72 (1.69) | 20.28 (3.32) | 20.6 (9.37) | 25.2 (3.99) | 16.12-150 (3.8) | 24.02 (4.54) | 26.66 (4.9) | 49.57 (8.04) | 47.32 (6.15) | 49.45 (6.19) | 49.34 (5.8) | |||||
All results are means (SE) in seconds.
↵2-150 p<0.05.