Table 2

Macroscopic cerebral infarction in a single cerebral hemisphere in UDV and DV groups and prevalence of microscopic vascular changes

Undemented
vascular disease (UDV)
Demented
vascular disease (DV)
% Cerebral hemisphere infarcted1.93 2.48
Single cerebral infarct present11††  3
Multiple cerebral infarcts present 4 8
No macroscopic cerebral infarct present 413
Microscopic vascular changes:
 Any cribriform change (n (%))12 (63) 22 (92)2-150
 Severe cribriform change (score 2/3, n (%)) 3 (16) 7 (71)**
 Microinfarction (n (%)) 5 (26)15 (63) ***
Congophilic angiopathy (n (%)) 4 (21) 8 (33)
  • 2-150 P=0.03 v UDV group; **P=0.0006 v UDV group; ***P=0.031 v UDV group; P=0.0067v C group (nil congophilic angiopathy); ††P=0.014, more prevalent than in DV; P=0.034, more prevalent than in UDV.

  • All analyses by Fisher’s exact test.