Table 1

Metabolite values (relative to the unsuppressed water peak) of control subjects and patients with multiple sclerosis at the beginning of the study

Ins
(Mean (SEM))
Cho
(Mean (SEM))
Cr
(Mean (SEM))
NAA
(Mean (SEM))
Treated patients4.73 (0.28)1-150 5.25 (0.22)5.69 (0.33)7.49 (0.31)**
WM lesions4.80 (0.19)1-150 5.41 (0.17)5.55 (0.20)7.15 (0.19)**
Untreated patients4.88 (0.28)1-150 5.56 (0.28)5.41 (0.26)6.82 (0.18)**
Treated patients4.19 (0.35)5.43 (0.23)5.60 (0.15)8.48 (0.10)
NAWM4.15 (0.21)5.33 (0.23)5.95 (0.19)8.63 (0.14)
Untreated patients4.12 (0.31)5.23 (0.43)6.29 (0.27)8.77 (0.27)
Control subjects3.97 (0.19)5.01 (0.24)5.77 (0.26)8.99 (0.40)
  • 1-150 p < 0.05; ** p < 0.0001 v control subjects.

  • WM = white matter; NAWM = normal appearing white matter.