Laboratory results of borrelia tests and interval between onset of symptoms and antibiotic treatment of three patients with Lyme borreliosis associated with intracranial aneurysms
| Patient No | |||
|---|---|---|---|
| 1 | 2 | 3 | |
| Serum antibodies | − | − | + |
| Proliferation of PBMC | ND | + | ND |
| CSF antibodies (intrathecally produced) | − | − | + |
| CSF PCR | − | − | − |
| Plasma PCR | + (×2) | + (×2) | − |
| Brain tissue PCR | − | ND | ND |
| Interval between onset of symptoms and treatment for Lyme borreliosis (months) | >13 | 5 | 12 |
PBMC = peripheral blood mononuclear cells; PCR = polymerase chain reaction; + = positive; − = negative; ND = not done; (×2) = from two specimens obtained and analysed at different times.