Table 3

Regional cerebral blood flow, oxygen extraction fraction, cerebral metabolic rate for oxygen, and cerebral blood volume in the control, silent brain infarction (SBI), and brain infarction (BI) groups

Cerebral cortexDeep grey matter
FrontalTemporalParietalOccipitalStriatumThalamus
rCBF (ml/100 g/min):
 Control35.7 (7.5)35.8 (6.5)37.2 (5.8)35.3 (7.0)43.4 (9.6)43.5 (9.6)
 SBI31.3 (6.4)30.8 (5.1)3-150 32.0 (6.3)3-150 32.3 (5.0)36.5 (7.6)3-150 32.2 (5.1)**
 BI29.6 (4.7)** 30.8 (4.8)** 31.9 (5.5)** 30.7 (5.3)3-150 35.6 (5.8)** 32.2 (5.3)**
rOEF:
Control 0.40 (0.04)0.40 (0.04)0.42 (0.05)0.44 (0.05)0.41 (0.05)0.36 (0.04)
 SBI0.43 (0.05)0.45 (0.06)3-150 0.43 (0.05)0.47 (0.06)0.43 (0.07)0.39 (0.06)
 BI0.43 (0.05)0.43 (0.05)0.44 (0.05)0.45 (0.05)0.42 (0.05)0.36 (0.05)
rCMRO2(ml/100 g/min):
Control 2.34 (0.29)2.39 (0.26)2.58 (0.37)2.59 (0.33)2.97 (0.46)2.55 (0.42)
 SBI2.22 (0.31)2.31 (0.32)2.32 (0.36)2.57 (0.46)2.62 (0.57)2.10 (0.26)**
 BI2.18 (0.31)2.30 (0.28)2.38 (0.27)2.40 (0.37)2.55 (0.34)** 1.99 (0.39)**
rCBV (ml/100 g):
Control 3.38 (0.62)3.68 (0.81)3.11 (0.47)3.82 (1.52)3.06 (0.55)3.80 (1.03)
 SBI2.85 (0.81)3-150 3.00 (0.65)** 2.70 (0.57)3-150 3.51 (1.23)2.75 (0.67)3.05 (0.87)3-150
 BI2.80 (0.41)** 3.18 (0.47)3-150 2.73 (0.38)3-150 3.69 (1.52)2.87 (0.52)3.44 (0.69)
rCBF/rCBV:
Control 10.7 (2.12)10.1 (2.60)12.1 (2.53)9.98 (2.67)14.4 (2.57)11.7 (2.20)
 SBI11.7 (3.42)10.8 (3.19)12.5 (3.88)10.3 (3.68)13.8 (3.69)11.5 (3.88)
 BI10.7 (1.57)9.88 (1.83)11.8 (2.40)9.31 (2.88)12.6 (2.48)9.70 (2.29)
  • 3-150 p<0.05; **p<0.01 v control group.

  • rCBF=regional cerebral blood flow; rOEF=regional oxygen extraction fraction; rCMRO2=regional cerebral metabolic rate for oxygen; rCBV=regional cerebral blood volume.