Table 2

Mean grain density/1000 μm2 (mean (SEM)) for DAT mRNA in regions of control and Parkinson’s disease ventral mesencephalon

ControlParkinson’s disease
PN775.6 (139.9)440.9 (46.8)
SNpc-dorsal625.5 (103)456 (70.6)2-151
SNpc-ventral760.1 (66)
PL691.6 (112.7)466.9 (83.4)
Background15.8 (3)12 (2)
  • 2-151 This value represents the mean from a region including dorsal and ventral tiers of SNpc.

  • PN=paranigral nucleus; SNpc=substantia nigra pars compacta; PL=pars lateralis.