Course of lipid storage myopathies during pregnancy and after delivery

NoAge1-150Myopathy1-150Muscle biopsyTime delivery to peak of weaknessCarnitine1-151Therapy and outcomeReference
PlasmaMuscle
119Deterioration after deliveryLSM5 monthsND4%No therapy
Death within 1 year		Boudin et al 19766
226Deterioration after deliveryLSMNGND25%No therapy
Death within 2 years		Cornelio et al 19774
316Manifestation after deliveryLSM6 months50%15%Carnitine supplementation
Improvement of weakness		Angelini et al 19787
424Manifestation after deliveryLSM9 monthsNormal47%Carnitine supplementation
No effect		Case reported here

  • ↵1-150 At pregnancy.

  • ↵1-151 Compared with healthy controls as given by the authors.

  • ND=not determined; NG=not given; LSM=lipid storage myopathy.