Patient | Age (y) | Sex | Clinical symptoms | Aetiology of facial palsy | Duration before treatment (y) | Injection sessions (n) | Dose of injected toxin in different injection sessions (range (mu)) | Range of clinical effect on synkinesia (S) and hyperlacrimation (H) | Mean difference (%) | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 67 | F | A: Yes | Idiopathic | ? | 2 | 60–120 | S: 4 | — | ||||
B: No | |||||||||||||
C: No | |||||||||||||
2 | 85 | F | A: Yes | Idiopathic | 2 | 8 | 40–120 | S: 2–4 | +57 | ||||
B: No | |||||||||||||
C: No | |||||||||||||
3 | 58 | F | A: Yes | Idiopathic | 30 | 5 | 60–120 | S: 4 | — | ||||
B: Yes | H: 1–2 | ||||||||||||
C: No | |||||||||||||
4 | 74 | F | A: Yes | Idiopathic | 1 | 1 | 70 | S: 3 | — | ||||
B: Yes | H: 2 | ||||||||||||
C: No | |||||||||||||
5 | 80 | F | A: Yes | Idiopathic | 1 | 5 | 60–100 | S: 2–4 | +47 | ||||
B: No | |||||||||||||
C: No | |||||||||||||
6 | 70 | M | A: Yes | Zoster oticus | 5 | 70–80 | S: 2–4 | +45 | |||||
B: Yes | H: 2 | ||||||||||||
C: No | |||||||||||||
7 | 68 | M | A: Yes | Resection of acusticus neurinoma | 7 | 1 | 80 | S: 3 | +67 | ||||
B: Yes | H: 1 | ||||||||||||
C: No | |||||||||||||
8 | 31 | F | A: Yes | Idiopathic | 5 | 2 | 80–100 | S: 4 | +26 | ||||
B: Yes | H: 2 | ||||||||||||
C: No | |||||||||||||
9 | 34 | F | A: Yes | Idiopathic | 4 | 1 | 60 | S: 4 | — | ||||
B: Yes | H: 2 | ||||||||||||
C: No | |||||||||||||
10 | 26 | F | A: Yes | Idiopathic | 4 | 2 | 60 | S: 4 | +40 | ||||
Hypolacrimation | H: No clinical effect on hypolacrimation | ||||||||||||
C: No |
Videographic assessment of the width of the affected lid was performed before and 2–4 weeks after the BTX A injection in patients 2, 5, 6, 7, 8, and 10.
A=synkinesias; B=hyperlacrimation; C=gustatory sweating.
Mean difference=mean difference between relative width of affected lid before and 2–4 weeks after treatment vunaffected side.