Table 1

Warm and cold perception thresholds in 20 patients with familial dysautonomia and 90 controls at six different body sites

SitePatients (n=20)
(mean (SD))
Controls (n=90) (mean (SD)
Cold threshold:
Thenar14.0 (8.4)1.9 (0.8)
 Arm13.8 (10.2)1.3 (0.8)
 Cheek10.2 (7.5)1.4 (0.4)
 Calf14.0 (9.8)2.8 (1.9)
 Foot15.3 (10.3)2.9 (1.6)
 Shoulder12.0 (8.2)1.4 (0.7)
Warm threshold:
 Thenar8.3 (3.3)1.4 (0.6)
 Arm8.1 (4.0)2.2 (1.5)
 Cheek6.6 (4.4)0.9 (0.3)
 Calf9.3 (4.0)3.5 (2.2)
 Foot8.5 (4.4)3.0 (1.9)
 Shoulder6.9 (3.6)1.8 (1.0)
  • In patients with familial dysautonomia all thresholds were significantly higher than in the control group (Mann-WhitneyU test, p<0.005).