Comparison of clinical features in the present cases and previous cases of PROMM with leukoencephalopathy reported by Hund et al13
| Clinical features | Present cases | Previous cases (n=6) with leukoencephalopathy | |||
|---|---|---|---|---|---|
| 1-1 | 2-1 | 2-2 | |||
| Age (y) | 49 | 28 | 17 | 33-62 | |
| Age at onset | 34 | — | — | 3-6th decades | |
| Weakness | Moderate | Mild | Mild | Mild to severe | |
| Muscular hypertrophy | Yes | Yes | Yes | Not reported | |
| Myotonia (clinical) | Mild | Mild | Mild | Mild | |
| Cataracts | Yes | No | No | Yes | |
| White matter changes | Yes | No | No | Yes | |
| IQ | 76 | NT | NT | NT | |