Sensitivity to clinical deterioration (per 10 UPDRS points, (95% CIs)) and estimated point of symptom onset (95% CIs) for each PET method and structure
| Structure (method of analysis) | Intercept as % normal mean | Sensitivity as % normal mean |
|---|---|---|
| Mean putamen (Ki) | 75 (14) (80%) | 7.4 (3.7) (7.2%) |
| Mean caudate (Ki) | 91 (12) (93%) | 4.3 (2.6)(3.6%) |
| Mean total striatum (Ki) | 89 (12)(86%) | 5.5 (3.2) (4.7%) |
| Mean putamen (ratio) | 88 (9) (89%) | 4.6 (2.5) (4.2%) |
| Mean caudate (ratio) | 96 (8) (96%) | 3.3 (1.8)(3.8%) |
Results in italics exclude 13 patients given entacapone before PET scanning.