Clinical characteristics of control subjects and patients with Alzheimer’s disease (AD) according to ε4 allele
| Patients with AD | Controls (n=8) | ||||
|---|---|---|---|---|---|
| 2 ε4 (n=8) | 1 ε4 (n=13) | 0 ε4 (n=10) | all AD (n=31) | ||
| Women/men | 3/5 | 5/8 | 6/4 | 14/17 | 5/3 |
| Familial/sporadic | 3/5 | 4/9 | 7/3 | 14/17 | |
| Age (y) | 65 (8) | 75 (7)1-150 | 70 (11) | 71 (9) | 74 (5)1-150 |
| Age at onset (y) | 59 (8) | 69 (7)1-150 | 64 (10) | 64 (9) | |
| Duration (y) | 6 (2) | 6 (2) | 6 (1) | 6 (2) | |
| Education (y) | 7 (1) | 8 (5) | 7 (2) | 7 (3) | 9 (2) |
| MMSE base line | 21 (3) | 22 (4) | 23 (4) | 22 (4) | 28 (2)*** |
| MMSE follow up | 15 (5) | 17 (5) | 16 (8) | 16 (6) | 29 (1)*** |
↵1-150 p<0.05 v 2 ε4, ANOVA; ***p<0.001v all other groups, ANOVA.
Values are expressed as mean (SD).