Table 2

Regional cerebral blood flow related to cerebellum: control subjects and subgroups with Alzheimer’s disease (AD) according to the number of the ε4 alleles

Patients with ADControl subjects (n=8)
2 ε4 (n=8)1 ε4 (n=13)0 ε4 (n=10)all AD (n=31)
Right frontal cortex:
Baseline0.87 (0.07)0.89 (0.09)0.84 (0.10)0.87 (0.09)0.87 (0.07)
 Follow up0.81 (0.11)0.85 (0.10)0.76 (0.15)0.81 (0.12)0.89 (0.05)
Left frontal cortex:
Baseline0.83 (0.09)0.85 (0.10)0.80 (0.12)0.83 (0.10)0.85 (0.03)
 Follow up0.79 (0.10)0.81 (0.10)0.72 (0.17)0.78 (0.13)0.85 (0.07)
Right temporal cortex:
Baseline0.85 (0.04)2-150 0.84 (0.05)2-150 0.86 (0.04)2-150 0.85 (0.04)2-150 0.90 (0.04)
 Follow up0.78 (0.06)0.81 (0.08)0.84 (0.10)0.81 (0.06)2-150 0.88 (0.06)
Left temporal cortex:
Baseline0.80 (0.08)0.82 (0.07)0.80 (0.12)0.81 (0.09)2-150 0.88 (0.05)
 Follow up0.73 (0.09)0.77 (0.11)0.77 (0.14)0.76 (0.11)2-150 0.85 (0.04)
Right parietal cortex:
Baseline0.80 (0.06)0.84 (0.07)0.84 (0.04)0.83 (0.06)2-150 0.88 (0.04)
 Follow up0.76 (0.05)2-150 0.79 (0.08)2-150 0.79 (0.10)2-150 0.78 (0.05)2-150 0.88 (0.05)
Left parietal cortex:
Baseline0.75 (0.08)0.80 (0.08)0.81 (0.10)0.79 (0.09)2-150 0.86 (0.04)
 Follow up0.72 (0.07)2-150 0.73 (0.10)2-150 0.75 (0.13)2-150 0.73 (0.10)2-150 0.87 (0.04)
Right occipital cortex:
Baseline0.91 (0.08)0.93 (0.07)0.95 (0.06)0.93 (0.07)0.92 (0.04)
 Follow up0.84 (0.10) 2-150 0.89 (0.06)0.95 (0.06)0.90 (0.08)0.94 (0.05)
Left occipital cortex:
Baseline0.88 (0.09)0.90 (0.08)0.96 (0.07)0.92 (0.08)0.91 (0.07)
 Follow up0.82 (0.07) 2-150 0.86 (0.10) 0.94 (0.07)0.87 (0.10)0.92 (0.05)
  • 2-150 p<0.05 v controls, v 0 ε4 subgroup, ANOVA.

  • Values are expressed as mean (SD).