Cox regression model fitted to all patients (n=236) with malignant glioma showing effect of each prognostic variable after adjusting for all others
| Covariate | Hazard ratio (95% CI) | p Value |
|---|---|---|
| MRC score: | ||
| 1–10 | 1 | <0.0001 |
| 11–15 | 5.00 (1.94–12.9) | |
| 16–20 | 6.54 (2.65–16.1) | |
| 21–25 | 7.30 (2.92–18.2) | |
| 26–33 | 11.2 (4.59–27.6) | |
| 34–38 | 35.8 (13.9–92.0) | |
| Year: | ||
| 1989–91 | 1 | 0.0002 |
| 1992–94 | 0.65 (0.48–0.88) | |
| 1995 | 0.28 (0.12–0.62) | |
| GBM v AA: | ||
| 0–1 y | 1.84 (1.19–2.88) | <0.0001 |
| 1–2 y | 3.65 (1.80–7.42) | |
| >2 y | 26.4 (5.35–130) | |
| Male v female | 1.27 (0.93–1.73) | 0.132 |
p Values shown are based upon the likelihood ratio test for the deletion of each covariate from the full model. GBM = glioblastoma; AA = anaplastic astrocytoma.