Table 1

Clinical summary and MRI findings of the Wilson’s disease group

Patien t	Age/sex	Age of onset	Age at diag nosis	Symptoms and sign	MRI findings at diagnosis	Other findings
1	M/26	20	25	Dysarthria, dystonia, bradykinesia, rigidity, dysdiadochokinesia	HSI on T2W1 in basal ganglia, thalamus, midbrain, cerebral atrophy	K–F rings liver cirrhosis
2	M/14	14	14	Dysarthria, dysphagia, dystonia, bradykinesia, postural imbalance	HSI on T2W1 in basal ganglia, midbrain	K–F rings liver cirrhosis
3	M/39	28	31	Dysarthria, dysphagia, dystonia, tremor	HSI on T2W1 in thalamus, midbrian, thalamus, pons, cerebral , and cerebellar white matter. Diffuse atrophy	K–F rings
4	F/21	17	20	Dysarthria, dystonia, bradykinesia, tremor, ataxic gait, dysdiadochokinesia	HSI on T2W1 in thalamus, midbrain, pons, middle cerebellar peduncles, basal ganglia	K–F rings liver cirrhosis
5	F/50	46	47	Rigidity, tremor, dysdiadochokinesia, shuffling gait	LSI on T2W1 in putamen and substantia nigra	K-F rings
6	M/31	12	12	Dysarthria, tremor, rigidity, bradikinesia	Not available	K–F rings

LSI=low signal intensity; HSI=high signal intensity; T2WI=T2 weighted images. MR imaging was performed with a Signa 1.5T system (General Electric, USA). T2 weighted images were obtained with spin echo technique with TR/TE=4000 to 5000/84 to 90.