Mean scores for main outcome measures
| Treatment group | Age | Estimated premorbid IQ (NART-R) | Current IQ (WAIS-R) | General memory (WMS-R) | Delayed memory (WMS-R) |
|---|---|---|---|---|---|
| TF+RT | 50.0 | 110.9 | 116.4 | 106.2 | 106.7 |
| TS+RT | 50.0 | 101.3 | 106.1 | 100.1 | 95.1 |
| TS only | 49.7 | 101.3 | 104.7 | 99.5 | 95.6 |
| RT only | 51.1 | 94.9 | 96.1 | 94.7 | 94.2 |
| Bromocriptine | 43.7 | 106.4 | 114.6 | 109.3 | 109.9 |
| Controls | 50.5 | 105.9 | 114.3 | 118.1 | 120.5 |
| F | n.s | n.s | p<0.002 | p<0.002 | p<0.001 |
| Analysis covaried for premorbid IQ | — | — | n.s | p<0.002 | p<0.001 |
TF+RT = Transfrontal hypophysectomy and radiotherapy; TS+RT=trans-sphenoidal hypophysectomy and radiotherapy; TS only = trans-sphenoidal hypophysectomy only; RT only = Radiotherapy only; bromocriptine=bromocriptine drug treatment only in the absence of surgery or radiotherapy; controls=selected where possible from the family and friends of the patients