Patients with MND | Controls | p Value | |||||||
---|---|---|---|---|---|---|---|---|---|
Mean | SD | n | Mean | SD | n | ||||
Age (y) | 67.3 | 11.3 | 18 | 69.7 | 7.8 | 24 | NS | ||
Education (y) | 9.8 | 1.3 | 18 | 10.8 | 2.3 | 24 | NS | ||
NART I.Q. | 106.5 | 8.6 | 13 | 109.9 | 6.2 | 24 | NS | ||
Digit span: | |||||||||
Forwards | 6.4 | 1.1 | 17 | 6.8 | 1.0 | 24 | NS | ||
Reverse | 3.8 | 1.0 | 17 | 4.8 | 1.2 | 24 | p<0.05 | ||
Verbal fluency: | |||||||||
Letters | 25.1 | 11.5 | 13 | 45.2 | 9.9 | 24 | p<0.005 | ||
Categories | 91.5 | 30.4 | 13 | 113.7 | 19.4 | 24 | p<0.05 | ||
Graded naming test | 18.6 | 6.9 | 17 | 22.5 | 4.3 | 24 | p<0.1 | ||
Median | Range | n | Median | Range | n | p Value | |||
MMSE | 29 | 19–30 | 17 | 29.5 | 27–30 | 24 | p<0.1 | ||
Dementia rating scale | 139 | 100–144 | 17 | 141 | 135–144 | 24 | p<0.05 | ||
Clinical dementia rating | 0 | 0–2 | 18 | — | — | — | — | ||
Picture naming | 46 | 32–48 | 17 | 43.5 | 38–47 | 24 | NS | ||
Word-picture matching | 48 | 44–48 | 17 | 48 | 44–48 | 24 | NS | ||
Pyramids and palm trees | 50 | 44–52 | 17 | 52 | 46–52 | 24 | p<0.05 | ||
TROG | 78 | 59–80 | 17 | 80 | 73–80 | 24 | p<0.05 |
n=Number of patients tested in each group; NART=national adult reading test; MMSE=mini mental state examination; TROG=test for the reception of grammar; median scores and ranges are given for data that are not normally distributed.