Results of the bivariate analysis comparing demographic characteristics, risk factors for stroke, risk factors for dementia, severity of the neurological deficit at admission, stroke subtype, and cause of stroke between patients with medial temporal lobe atrophy MTLA (+) and patients without (MTLA −)
| Variables | MTLA (−) n=76 | MTLA (+) n=94 | OR (95 CI) | p Value |
|---|---|---|---|---|
| Demographic characteristics: | ||||
| Age (y)1-150 | 68.5 (42–91) | 79 (49–101) | <0.0001 | |
| Female sex1-151 | 35 (46.1) | 52 (55.3) | 1.5 (0.8–2.7) | 0.2295 |
| Primary education level1-151 | 63 (82.9) | 76 (80.9) | 0.9 (0.4–1.9) | 0.7315 |
| Loss of IDLA ()1-150 | 3 (0–92) | 17 (0–85) | <0.0001 | |
| Cognitive status before stroke: | ||||
| IQCODE score1-150 | 78 (78–128) | 88 (78–130) | <0.0001 | |
| Possible risk factors for stroke: | ||||
| Smokers1-151 | 18 (23.7) | 13 (13.8) | 0.5 (0.2–1.1) | 0.0980 |
| Alcoholism1-151 | 21 (27.6) | 14 (14.9) | 0.5 (0.2–1) | 0.0412 |
| Arterial hypertension1-151 | 43 (56.6) | 52 (54.2) | 1 (0.5–1.8) | 0.8694 |
| Diabetes mellitus1-151 | 6 (7.9) | 16 (17) | 2.4 (0.9–6.5) | 0.0780 |
| Hyperlipidaemia1-151 | 18 (23.7) | 19 (20.2) | 0.8 (0.4–1.7) | 0.5855 |
| Migraineurs1-151 | 10 (13.2) | 11 (11.7) | 0.9 (0.4–2.2) | 0.7742 |
| History of atrial fibrillation1-151 | 12 (15.8) | 25 (26.6) | 1.9 (0.9–4.2) | 0.0896 |
| Coronary heart disease1-151 | 18 (23.7) | 36 (38.3) | 2 (1–3.9) | 0.0419 |
| Peripheral artery disease1-151 | 10 (13.2) | 9 (9.6) | 0.7 (0.3–1.8) | 0.4610 |
| Familial stroke1-151 | 27 (35.5) | 31 (33) | 0.9 (0.5–1.7) | 0.7276 |
| Familial migraine1-151 | 11 (14.5) | 11 (11.7) | 0.8 (0.3–1.9) | 0.5925 |
| Possible risk factors for dementia: | ||||
| History of depression1-151 | 15 (19.7) | 10 (10.6) | 0.5 (0.2–1.2) | 0.0958 |
| Parkinson’s disease1-151 | 2 (2.6) | 2 (2.1) | 0.8 (0.1–5.9) | 0.6059 |
| Thyroid disorders1-151 | 6 (7.9) | 4 (4.3) | 0.5 (0.1–1.9) | 0.2491 |
| Familial dementia1-151 | 10 (13.2) | 13 (13.8) | 1 (0.4–2.6) | 0.8987 |
| Familial depression1-151 | 16 (21.1) | 20 (21.3) | 1 (0.5–2.1) | 0.4716 |
| Previous stroke or TIA1-151 | 22 (28.9) | 24 (25.5) | 0.8 (0.4–1.7) | 0.6182 |
| Stroke characteristics: | ||||
| Orgogozo score at admission1-150 | 70 (10–100) | 70 (5–100) | — | 0.6946 |
| Ischaemic stroke1-151 | 68 (89.5) | 84 (89.4) | 1 (0.4–2.7) | 0.9812 |
| Cervical artery atheroma1-151 | 16 (21.1) | 21 (22.3) | 1.1 (0.5–2.3) | 0.8397 |
| Cardioembolism1-151 | 15 (19.7) | 27 (28.7) | 1.6 (0.8–3.4) | 0.1768 |
| Lipohyalinosis1-151 | 11 (14.5) | 12 (12.8) | 0.9 (0.4–2.1) | 0.7462 |
| Other definite causes1-151 | 1 (1.3) | 1 (1.1) | 0.8 (0.1–13.2) | 0.6957 |
| Undetermined cause1-151 | 3 (3.9) | 7 (7.4) | 2 (0.5–7.9) | 0.2656 |
| Unknown cause1-151 | 28 (36.8) | 24 (25.5) | 0.6 (0.3–1.1) | 0.1116 |
| CT findings: | ||||
| Leukoaraiosis score1-150 | 0 (0–3) | 1 (0–3) | 0.0004 | |
| Cerebral atrophy score1-150 | 1 (0–3) | 2 (0–3) | <0.0001 | |
| At least 1 old infarct1-151 | 28 (36.8) | 35 (37.2) | 1.0 (0.6–1.8) | 0.9580 |
| Anterior superficial infarct1-151 | 1 (1.3) | 3 (3.2) | 2.4 (0.3–24.0) | 0.4224 |
| Posterior superficial infarct1-151 | 3 (3.9) | 5 (5.3) | 1.4 (0.3–5.9) | 0.6745 |
| Superficial infarct1-151 | 4 (5.3) | 8 (8.5) | 1.6 (0.5–5.6) | 0.4111 |
| Deep infarct1-151 | 23 (30.3) | 26 (27.7) | 0.9 (0.5–1.7) | 0.7094 |
| Cerebellum-brainstem1-151 | 4 (5.3) | 4 (4.3) | 0.8 (0.2–3.4) | 0.7577 |
| Right hemisphere1-151 | 20 (26.3) | 28 (29.8) | 1.1 (0.6–2.2) | 0.6171 |
| Left hemisphere1-151 | 16 (21.1) | 20 (21.3) | 1.0 (0.5–2.1) | 0.9717 |
| Bilateral infarcts1-151 | 10 (13.2) | 26 (17) | 1.3 (0.6–3.0) | 0.4865 |
| At least 1 silent infarct1-151 | 21 (27.6) | 34 (36.2) | 1.3 (0.7–2.4) | 0.6960 |